Michel nussenzweig rockefeller

This work has helped establish a new paradigm for developing vaccines and therapies for infectious diseases. This paradigm has been extended to other viruses such as hepatitis B and flaviviruses. In response to the COVID outbreak, Nusssenzweig has extended this research to SARS-CoV-2 and is working to isolate and characterize highly potent neutralizing antibodies from patients who have recovered from the disease.

Current studies focus on outlining the pathway of human dendritic cell development and differentiation. During inflammation or infection, dendritic cells present self-antigens simultaneously with non-self-antigens. By establishing tolerance to self-antigens before challenge with pathogens, dendritic cells can focus the adaptive immune system entirely on the pathogen, thereby avoiding autoimmunity.

The ability to target antigens to dendritic cells and control their function in vivo has significant implications for the development of vaccines and therapies for autoimmunity.

Michel nussenzweig rockefeller: Michel C. Nussenzweig is a

Recently, the lab defined distinct progenitor lineages for classical spleen dendritic cells, plasmacytoid dendritic cells, and monocytes, a step toward antigen-specific targeting. Internship and Residency in medicine, — Fellowship in infectious diseases, — Massachusetts General Hospital. MacLean, A. Affinity maturation of antibody responses is mediated by plasma cell proliferation.

Scienceeadr Schaefer-Babajew, D. Nature— Muecksch, F. Gaebler, C. Prolonged viral suppression with anti-HIV-1 antibody therapy. Merkenschlager, J. Dynamic regulation of TFH selection during the germinal centre reaction. Michel C. Nussenzweig, M. Zanvil A. References [ edit ]. Scholia has an author profile for Michel C. The Journal of Experimental Medicine.

ISSN PMC PMID Bibcode : PNAS The Rockefeller University. Retrieved 16 Aug Howard Hughes Medical Institute. Bibcode : Natur.

Michel nussenzweig rockefeller: Nussenzweig, Michel C. Investigator, Howard

S2CID Bibcode : Sci Retrieved 14 July Retrieved 15 August Retrieved 18 July News from The National Academies. Nussenzweig elected to National Academy of Sciences". Retrieved 16 August The Official Site of the Nobel Prize. Retrieved 18 September Real Academia Nacional de Farmacia in Spanish. The American Association of Immunologists. Retrieved 7 March Journal of Experimental Medicine.

Michel nussenzweig rockefeller: Nussenzweig's laboratory studies the

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